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Home / Proteins & Peptide

Recombinant Human Tumor necrosis factor receptor superfamily member 10C(TNFRSF10C),partial (Active)

SKU : BHP10506448

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-AP004981HU
Alternative Names	Tumor Necrosis Factor Receptor Superfamily Member 10C, Antagonist Decoy Receptor for TRAIL/Apo-2L, Decoy TRAIL Receptor Without Death Domain, Decoy Receptor 1, DcR1, Lymphocyte Inhibitor of TRAIL, TNF-Related Apoptosis-Inducing Ligand Receptor 3, TRAIL Receptor 3, TRAIL-R3, TRAIL Receptor Without an Intracellular Domain, CD263, TNFRSF10C, DCR1, LIT, TRAILR3, TRID
Source	Mammalian cell
Endotoxin Level	Less than 1.0 EU/μg as determined by LAL method.
Bioactivity	The ED50 as determined by its ability to inhibit TRAIL-mediated cytotoxicity using L?929 mouse fibroblast cells treated with TRAIL is typically 450 ng/mL.
Expression Region	26-221aa
Mol Weight	48.7 kDa
Protein Description	Partial

Subcellular Location	Cell membrane, Lipid-anchor, GPI-anchor
Uniprot	O14798
Database Links	HGNC:11906 OMIM:603613 KEGG:hsa:8794 STRING:9606.ENSP00000349324 UniGene:Hs.655801
Function	Receptor for the cytotoxic ligand TRAIL. Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. May protect cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.
Pathway	Apoptosis; Necroptosis; Natural killer cell mediated cytotoxicity
Research Area	Cancer
Tissue Specificity	Higher expression in normal tissues than in tumor cell lines. Highly expressed in peripheral blood lymphocytes, spleen, skeletal muscle, placenta, lung and heart.

Purity	Greater than 95% as determined by SDS-PAGE.
Storage Buffer	Lyophilized from a 0.2 μm filtered 20 mM PB, 150 mM NaCl, pH 7.4

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10506448	CSB-AP004981HU	1mg	$1644		Add to Cart
BHP10506448	CSB-AP004981HU	500ug	$1256		Add to Cart
BHP10506448	CSB-AP004981HU	50ug	$290		Add to Cart

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