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Home / Proteins & Peptide

Recombinant Human Tumor necrosis factor ligand superfamily member 18 protein(TNFSF18) (Active)

BHP10500226
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Contact us to order
Tel
+1 866.986.9598
Email
[email protected]
Get a Quote
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Subcellular Location Cell membrane, Single-pass type II membrane protein
Uniprot Q9UNG2, Q9UNG2
Database Links

HGNC:11932

OMIM:603898

KEGG:hsa:8995

STRING:9606.ENSP00000385470

UniGene:Hs.248197
Function Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B. Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1
Protein Families Tumor necrosis factor family
Research Area Cancer
Tissue Specificity Expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells.
Weight 14.3 kDa
Buffer 0.2 m filtered PBS, pH 7.4,lyophilized
Purity >98% as determined by SDS-PAGE and HPLC.
Storage Buffer 0.2 m filtered PBS, pH 7.4 ,lyophilized
Immunogen Species Homo Sapiens (Human)
SKU Supplier No. Size Your price Quantity
BHP10500226 CSB-AP002351HU 500ug $4536
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BHP10500226 CSB-AP002351HU 100ug $2022
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BHP10500226 CSB-AP002351HU 5ug $142
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