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Home / Proteins & Peptide

Recombinant Human Transmembrane emp24 domain-containing protein 9(GP25L2) ,partial

SKU : BHP10501798

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-RP048044h
Alternative Names	GMP25Glycoprotein 25L2p24 family protein alpha-2 ,p24alpha2p25, GMP25Glycoprotein 25L2p24 family protein alpha-2 ; p24alpha2p25
Tag	N-terminal GST-tagged
Regulatory	RUO
Relevance	Appears to be involved in vesicular protein trafficking, mainly in the early secretory pathway. In COPI vesicle-mediated retrograde transport involved in the coatomer recruitment to mbranes of the early secretory pathway. Increases coatomer-dependent activity of ARFGAP2. Thought to play a crucial role in the specific retention of p24 complexes in cis-Golgi mbranes; specifically contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network. May be involved in organization of intracellular mbranes, such as of the ER-Golgi intermediate compartment and the Golgi apparatus. Involved in ER localization of PTPN2 isoform PTPB.
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Expression Region	40-197aa
Mol Weight	45.5kDa
Nature	recombinant
Protein Description	Partial

Subcellular Location	Endoplasmic reticulum membrane, Single-pass type I membrane protein, Golgi apparatus, cis-Golgi network membrane, Single-pass type I membrane protein, Endoplasmic reticulum-Golgi intermediate compartment membrane, Single-pass type I membrane protein, Golgi apparatus, trans-Golgi network membrane, Single-pass type I membrane protein
Uniprot	Q9BVK6, Q9BVK6
Database Links	HGNC:24878 KEGG:hsa:54732 STRING:9606.ENSP00000330945 UniGene:Hs.279929
Function	Appears to be involved in vesicular protein trafficking, mainly in the early secretory pathway. In COPI vesicle-mediated retrograde transport involved in the coatomer recruitment to membranes of the early secretory pathway. Increases coatomer-dependent activity of ARFGAP2. Thought to play a crucial role in the specific retention of p24 complexes in cis-Golgi membranes; specifically contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network. May be involved in organization of intracellular membranes, such as of the ER-Golgi intermediate compartment and the Golgi apparatus. Involved in ER localization of PTPN2 isoform PTPB.
Protein Families	EMP24/GP25L family
Research Area	Signal Transduction
Weight	45.9kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10501798	CSB-RP048044h	1mg	$1812		Add to Cart
BHP10501798	CSB-RP048044h	100ug	$419		Add to Cart
BHP10501798	CSB-RP048044h	20ug	$224		Add to Cart

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