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Home / Proteins & Peptide

Recombinant Human Tie2/CD202b Protein (His Tag)(Active)

SKU : BHP10302977

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH031472
Description	A DNA sequence encoding the extracellular domain (Met 1-Lys 745) of human Tie2 (NP_000450.2) precursor was fused with a polyhistidine tag at the C-terminus.
Alternative Names	CD202B;TIE-2;TIE2;VMCM;VMCM1
Reconstitution	Please refer to the printed manual for detailed information.
Background	TEK, or TIE-2, is an endothelial cell-specific receptor tyrosine kinase (RTK) that is known as a functioning molecule of vascular endothelial cells. TEK comprises a subfamily of RTK with TIE, and these two receptors play critical roles in vascular maturation, maintenance of integrity and remodeling. Targeted mutagenesis of both Tek and its agonistic ligand, Angiopoietin-1, result in embryonic lethality, demonstrating that the signal transduction pathways mediated by this receptor are crucial for normal embryonic development. TEK signaling is indispensable for the development of the embryonic vasculature and suggests that TEK signaling may also be required for the development of the tumor vasculature.
Reactivity	Human
Tag	C-His
Formulation	Lyophilized from sterile PBS, pH 7.4
Host	HEK293 Cells
Accession Number	NP_000450.2
Endotoxin Level	< 1.0 EU per ug as determined by the LAL method.
Bioactivity	Measured by its binding ability in a functional ELISA. Immobilized recombinant human Tie2 at 2 ug/ml (100 ul/well) can bind human Angiopoietin-2 at a linear range of 1.28-160 ng/ml.
Mol Weight	82 kDa
Mw(kda)	82 kDa

Sequence Info	Met 1-Lys 745

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 95 % as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10302977	PKSH031472	100ug	$535		Add to Cart
BHP10302977	PKSH031472	1mg	-		Add to Cart

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