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Home / Proteins & Peptide

Recombinant Human THPO

SKU : BHP10900789

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z101519
Description	Thrombopoietin, known also as TSF (thrombopoiesis stimulating factor), for mediator substances that function as natural stimulators of megakaryocytopoiesis and thus, promote the differentiation of platelets. Thrombopoietin stimulates an increase in the sizes and numbers of megakaryocytes. It also increases the number of small acetyl-cholinesterase positive cells that are early precursor cells of the megakaryocytic lineage. Thrombopoietin is a protein of 332 amino acids that shows significant homology with Epo (erythropoietin) in its N-terminal domain. A comparison of human and porcine Thrombopoietin sequences shows 83 % identity between the erythropoietin-like domains but only 67 % between the C- terminal domains.
Alternative Names	MGDF ; Myeloproliferative leukemia virus oncogene ligand ; C-mpl ligand ; ML ; Megakaryocyte colony-stimulating factor ; Megakaryocyte growth and development factor
Quantity	1.0 mg
Regulatory	RUO
Source	E. coli
Host	Human
Endotoxin Level	<1.0 EU/μg of recombinant protein as determined by the LAL method
Biological Activity Comment	The ED50 as determined by the dose-dependent proliferation of Mo7e cells was found to be in the range of 1-2 ng/mL

Weight	35.0 kDa

Description	A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Format	Lyophilized Powder Lyophilized from a 0.2 μm filtered solution in PBS (pH 7.0)
Purity	>95% as determined by SDS-PAGE
Storage	The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

MSDS	Growth Factors, Cytokines & Kinases MSDS
Other	Growth Factor and Cytokine Brochure

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900789	Z101519	1.0mg	$5300		Add to Cart

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