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Recombinant Human Thioredoxin(TXN)

BHP10506334
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Subcellular Location Nucleus, Cytoplasm, Secreted
Uniprot P10599
Database Links

HGNC:12435

OMIM:187700

KEGG:hsa:7295

STRING:9606.ENSP00000363641

UniGene:Hs.435136
Function Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.; FUNCTION
Pathway NOD-like receptor signaling pathway
Protein Families Thioredoxin family
Research Area Signal Transduction
Purity Greater than 95% as determined by SDS-PAGE.
Storage Buffer Lyophilized from a 0.2 μm filtered 20 mM PB, 150 mM NaCl, pH 7.2
Immunogen Species Homo Sapiens (Human)
SKU Supplier No. Size Your price Quantity
BHP10506334 CSB-AP005541HU 1mg $1064
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BHP10506334 CSB-AP005541HU 500ug $580
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BHP10506334 CSB-AP005541HU 50ug $154
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