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Home / Proteins & Peptide

Recombinant Human TGFBR1 (ALK5) (N-GST tag)

SKU : BHP10901116

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z500385
Description	TGFßR1 or transforming growth factor, beta-receptor 1 is a member of the TGFß receptor subfamily and is a ser/thr protein kinase that forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. Mutations in TGFßR1gene have been associated with Marfan syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors . TGFßR1-dependent signaling is required for angiogenesis but not for the development of hematopoietic progenitor cells and functional hematopoiesis .
Alternative Names	AAT5 ; ALK5 ; SKR4 ; ALK-5 ; LDS1A ; LSD2A ; TGFR-1 ; ACVRLK4
Tag	N-GST tag
Quantity	10 µg
Regulatory	RUO
Source	Insect cells
Host	Human
Biological Activity Comment	The specific activity of TGFßR1 was determined to be 3 nmol /min/mg as per activity assay protocol.

Weight	66.0 kDa

Format	Liquid 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Purity	70% - 90%
Storage	Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10901116	Z500385	10µg	$361.11		Add to Cart

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