Found in the gastrointestinal tract, the three Trefoil proteins, TFF1, 2, and 3 have been shown to play an important role in intestinal mucosal defence and repair. Specifically, TFF2 has been shown to inhibit gastrointestinal motility and secretion of the gastric acid.
Lyophilized from a 0.2 μm filtered solution in PBS
Molecular Weight
12.3 kDa
Quantity
100 µg
Source
E. coli
Usage
For research use only. Not for diagnostic or therapeutic use.
Accession Number
Q03403
Endotoxin Level
<1.0 EU/μg of recombinant protein as determined by the LAL method
Bioactivity
The ED(50) was determined by the dose-dependent proliferation of immortalized human pancreatic cells and was found to be <5ng/mL.,
Gel Image
Gene Id
7032
Gene Name
TFF2
Purity
>95% as determined by SDS-PAGE
Storage
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity.Avoid repeated freeze/thaw cycles.