Thymus and activation-regulated chemokine (TARC) is a recently identified CC chemokine that is expressed constitutively in the thymus and transiently in stimulated peripheral blood mononuclear cells. TARC functions as a selective chemoattractant for T cells that express a class of receptors binding TARC with high affinity and specificity. The chemokine TARC is a ligand for the chemokine receptor CCR4 expressed on CD4 Th2 cells.
<1.0 EU/μg of recombinant protein as determined by the LAL method.
Biological Activity Comment
Determined by its ability to chemoattract human T cells using a concentration range of 2-40 ng/mL.
Weight
8.0 kDa
Description
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Format
Lyophilized PowderLyophilized from a 0.2 μm filtered solution in PB,100 mM NaCl, pH 7.5.
Purity
>95% as determined by SDS-PAGE
Storage
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.