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Home / Proteins & Peptide

Recombinant Human SUMO1 Protein (His Tag)(Active)

SKU : BHP10302800

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH030730
Description	A DNA sequence encoding the human SUMO1 (AAH66306.1) (Ser 2-Val 101) was expressed, with a polyhistide tag at the N-terminus.
Alternative Names	Small Ubiquitin-Related Modifier 1; SUMO-1; GAP-Modifying Protein 1; GMP1; SMT3 Homolog 3; Sentrin; Ubiquitin-Homology Domain Protein PIC1; Ubiquitin-Like Protein SMT3C; Smt3C; Ubiquitin-Like Protein;UBL1; SUMO1; SMT3C; SMT3H3; UBL1;DAP1;OFC10;SENP2;SMT3
Reconstitution	Please refer to the printed manual for detailed information.
Background	Small ubiquitin-like modifier protein (SUMO) modification is a highly dynamic process, catalyzed by SUMO-specific activating (E1), conjugating (E2) and ligating (E3) enzymes, and reversed by a family of SUMO-specific proteases (SENPs). Small ubiquitin-like modifier 1 (SUMO1) is a member of the superfamily of ubiquitin-like proteins. Despite its structural similarity with ubiquitin, SUMO1 does not seem to play any role in protein degradation. SUMO1 plays an important role in modulation of NOX activity required for ROS generation. SUMO1 haploinsufficiency results in cleft lip and palate in animal models. SUMO1 gene variation in human non-syndromic cleft lip with or without cleft palate (NSCLP) development. SUMO-1 may be useful as a novel target for therapy in oral squamous cell carcinoma (SCC) as well as a clinical indicator for tumor recurrence together with Mdm2.
Reactivity	Human
Tag	N-His
Formulation	Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 7.5
Host	E.coli
Accession Number	AAH66306.1
Endotoxin Level	Please contact us for more information.
Bioactivity	Measured by its ability to be proteolytically processed by SENP1.>50% of 1 ug Recombinant Human (rh) SUMO1 is cleaved by < 10 ng of recombinant human SENP.
Mol Weight	12.4 kDa
Mw(kda)	12.4 kDa

Sequence Info	Ser 2-Val 101

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 90 % as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10302800	PKSH030730	50ug	$732		Add to Cart

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