STK19 is a member of the serine/threonine kinase family that shows a manganese-dependent protein kinase activity and phosphorylates a-casein at ser/thr residues and histone at ser residues. STK19 contains a positively charged putative nuclear localization signal, multiple potential phosphorylation sites, 2 amidation sites, 9 potential N-myristoylation sites, and no N-glycosylation sites. STK19 has been shown to localize predominantly in the nucleus . The phosphorylation of STK19 is thought to be involved in transcriptional regulation. STK19 localizes to the major histocompatibility complex (MHC) class III region on chromosome 6 .
Alternative Names
D6S60E ; G11 ; HLA-RP1 ; RP1 ; D6S60
Tag
N-GST tag
Quantity
10 µg
Regulatory
RUO
Source
Insect cells
Host
Human
Biological Activity Comment
The specific activity of STK19 was determined to be2 nmol /min/mg as per activity assay protocol
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.