SRMS is a Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites that is involved in proliferation or differentiation of keratinocytes in the skin. SRMS functions as a rapid downstream signaling intermediate following calcium-induced differentiation in keratinocytes. SRMS constitutes a new family of non-receptor tyrosine kinases that may be redundant in function . SRMS can act either in the membrane or at the nucleus, and may change localization patterns depending on external stimuli.
Alternative Names
C20orf148 ; dJ697K14.1 ; SRM
Tag
N-GST tag
Quantity
10 µg
Regulatory
RUO
Source
Insect cells
Host
Human
Biological Activity Comment
The specific activity of SRMS was determined to be 24 nmol /min/mg as per activity assay protocol.
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