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Home / Proteins & Peptide

Recombinant Human Small ubiquitin-related modifier 4(SUMO4)

SKU : BHP10503625

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP718803HU
Alternative Names	Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may modulate protein subcellular localization, stability or activity. Upon oxidative stress, conjugates to various anti-oxidant enzymes, chaperones, and stress defense proteins. May also conjugate to NFKBIA, TFAP2A and FOS, negatively regulating their transcriptional activity, and to NR3C1, positively regulating its transcriptional activity. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I.
Tag	N-terminal GST-tagged
Regulatory	RUO
Relevance	Small ubiquitin-like protein 4
Source	E.coli
Abbreviation	SUMO4
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Protein Name	Recommended name: Small ubiquitin-related modifier 4; Short name= SUMO-4; Alternative name(s): Small ubiquitin-like protein 4
Expression Region	1-95aa
Mol Weight	37.7kDa
Nature	recombinant
Protein Description	Full Length of BC130305

Uniprot	Q6EEV6, Q6EEV6
Database Links	HGNC:21181 OMIM:600320 KEGG:hsa:387082 STRING:9606.ENSP00000318635 UniGene:Hs.657168
Function	Ubiquitin-like protein which can be covalently attached to target lysines as a monomer. Does not seem to be involved in protein degradation and may modulate protein subcellular localization, stability or activity. Upon oxidative stress, conjugates to various anti-oxidant enzymes, chaperones, and stress defense proteins. May also conjugate to NFKBIA, TFAP2A and FOS, negatively regulating their transcriptional activity, and to NR3C1, positively regulating its transcriptional activity. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I.
Protein Families	Ubiquitin family, SUMO subfamily
Research Area	Cell Biology
Tissue Specificity	Expressed mainly in adult and embryonic kidney. Expressed at various levels in immune tissues, with the highest expression in the lymph node and spleen.
Weight	37.945kD

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10503625	CSB-EP718803HU	1mg	$1812		Add to Cart
BHP10503625	CSB-EP718803HU	100ug	$419		Add to Cart
BHP10503625	CSB-EP718803HU	20ug	$224		Add to Cart

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