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Home / Proteins & Peptide

Recombinant Human SLK (N-GST tag)

SKU : BHP10900483

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z500360
Description	SLK or LOSK is a Ste20-like protein kinase that associates with microtubule and centrosome. Inhibition of SLK activity by dominant-negative mutant or RNAi leads to unfocused microtubule arrangement indicating that SLK is needed for microtubule organization and for the proper localization of Golgi complex . Expression of v-Src can down-regulate SLK activity through the involvement of CK2 which can directly phosphorylate and inhibit SLK activity whereas inhibition of CK2 in v-Src-transformed cells results in normal SLK activity . CK2 and SLK can be co-localized in fibroblasts spreading on fibronectin-coated substrates.
Alternative Names	MGC133067 ; bA16H23.1 ; LOSK ; STK2 ; se20-9 ; KIAA0204
Tag	N-GST tag
Quantity	10 µg
Regulatory	RUO
Source	Insect cells
Host	Human
Biological Activity Comment	The specific activity of SLK was determined to be 4.6 nmol /min/mg as per activity assay protocol.

Weight	180.0 kDa

Format	Liquid 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Purity	70% - 90%
Storage	Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900483	Z500360	10µg	$361.11		Add to Cart

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