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Home / Proteins & Peptide

Recombinant Human SIK3 (N-GST tag)

SKU : BHP10900492

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z500359
Description	SIK3 (QSK) is a serine/threonine-protein kinase, belongs to QIK subfamily. The phosphorylation of SIK3 by LKB1 through the 14-3-3 binding enhances its catalytic activity and leads its localization to punctate structures within the cytoplasm . Overexpression of SIK3 promotes G1/S cell cycle progression with ovarian cancer . There are two sites (H331L and A1103V) were mutated at significant frequency in breast cancer (3). SIK3 is a novel tumor-associated antigen (TAA).
Alternative Names	SIK-3 ; L19 ; FLJ12240 ; KIAA0999 ; QSK
Tag	N-GST tag
Quantity	10 µg
Regulatory	RUO
Source	Insect cells
Host	Human
Biological Activity Comment	The specific activity of SIK3 was determined to be 140 nmol /min/mg as per activity assay protocol.

Weight	62.0 kDa

Format	Liquid 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Purity	70% - 90%
Storage	Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900492	Z500359	10µg	$361.11		Add to Cart

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