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Home / Proteins & Peptide

Recombinant Human SIGLEC5 Protein (Fc Tag)

SKU : BHP10302857

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH031000
Description	A DNA sequence encoding the human SIGLEC5 (O15389) (Met1-Thr 434) was expressed; fused with the Fc region of human IgG1 at the C-terminus.
Alternative Names	Sialic acid-binding Ig-like lectin 5; Siglec-5; CD33 antigen-like 2; Obesity-binding protein 2; OB-BP2; CD170;CD33L2;OB-BP2;OBBP;OBBP2;SIGLEC-5;SIGLEC5
Reconstitution	Please refer to the printed manual for detailed information.
Background	SIGLEC5 contains 2 Ig-like C2-type (immunoglobulin-like) domains and 1 Ig-like V-type (immunoglobulin-like) domain. It belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. SIGLEC5 is expressed by monocytic/myeloid lineage cells. It is found at high levels in peripheral blood leukocytes; spleen; bone marrow and at lower levels in lymph node; lung; appendix; placenta; pancreas and thymus. It is also expressed by monocytes and neutrophils but absent from leukemic cell lines representing early stages of myelomonocytic differentiation. SIGLEC5 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It binds equally to alpha-2;3-linked and alpha-2;6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
Reactivity	Human
Tag	C-Fc
Formulation	Lyophilized from sterile PBS; pH 7.4
Host	HEK293 Cells
Accession Number	O15389
Endotoxin Level	< 1.0 EU per ug as determined by the LAL method.
Mol Weight	73.4 kDa
Mw(kda)	73.4 kDa

Sequence Info	Met 1-Thr 434

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 90 % as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10302857	PKSH031000	100ug	$732		Add to Cart

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