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Home / Proteins & Peptide

Recombinant Human SerpinB6/PI-6 Protein (His Tag)

SKU : BHP10300352

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH030778
Description	A DNA sequence encoding the human SERPINB6 (AAB30320.1) (Asp 2-Pro 376) was expressed, with a polyhistidine tag at the N-terminus.
Alternative Names	RP1-90J20.6 ; CAP ; DFNB91 ; DKFZp686I04222 ; MGC111370 ; PI6 ; PTI ; SPI3 ; MSTP057
Background	SerpinB6, also known as Cytoplasmic antiproteinase, Peptidase inhibitor 6, Placental thrombin inhibitor, SERPINB6 and PI-6, is a cytoplasm protein which belongs to the serpin family and Ov-serpin subfamily. SerpinB6/ PI-6 is an inhibitor of cathepsin G, kallikrein-8 and thrombin. It may play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and sensorineural hearing loss. SerpinB6/ PI-6 is expressed in keratinocytes (at protein level). It is also found in placenta, cardiac muscle, lung, liver, kidney and pancreas. SerpinB6/ PI-6 is expressed in the inner ear hair cells. It expressed abundantly by normal mast cells in different tissues and by mast cells in mastocytoma lesions. SerpinB6/ PI-6 may be involved in the regulation of serine proteinases present in the brain or extravasated from the blood. Defects in SerpinB6 are the cause of deafness autosomal recessive type 91 which is a form of non-syndromic deafness characterized by progressive and age-dependent sensorineural hearing loss. Vestibular function is normal.
Tag	His tag
Regulatory	RUO
Host	Baculovirus-Insect Cells
Endotoxin Level	< 1.0 EU per μg of the protein as determined by the LAL method
Nature	Recombinant

Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Buffer	Lyophilized from sterile PBS, pH 7.4
Description	Please refer to the printed manual for detailed information.
Purity	> 90 % as determined by SDS-PAGE
Expiry Date	Samples are stable for up to twelve months from date of receipt at -70℃

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10300352	PKSH030778	50ug	$732		Add to Cart

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