Recombinant Human Serine/threonine-protein kinase PAK 5(PAK5),partial

Mfr.No.	CSB-BP885798HU
Alternative Names	p21-activated kinase 5, PAK-5, p21-activated kinase 7, PAK-7, p21-activated kinase 5 ; PAK-5 ; p21-activated kinase 7 ; PAK-7
Tag	N-terminal 6xHis-tagged
Regulatory	RUO
Relevance	Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, proliferation or cell survival. Activation by various effectors including growth factor receptors or active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates the proto-oncogene RAF1 and stimulates its kinase activity. Promotes cell survival by phosphorylating the BCL2 antagonist of cell death BAD. Phosphorylates CTNND1, probably to regulate cytoskeletal organization and cell morphology. Keeps microtubules stable through MARK2 inhibition and destabilizes the F-actin network leading to the disappearance of stress fibers and focal adhesions.
Source	Baculovirus
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Expression Region	1-293aa
Mol Weight	34.9kDa
Nature	recombinant
Protein Description	Partial

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

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SKU	Supplier No.	Size	Your price
BHP10504016	CSB-BP885798HU	500ug	$2112	Add to Cart
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BHP10504016	CSB-BP885798HU	20ug	$528	Add to Cart