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Home / Proteins & Peptide

Recombinant Human Semaphorin 5A/SEMA5A Protein (aa 23-765, His Tag)

SKU : BHP10304021

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH033024
Alternative Names	Semaphorin-5A; Semaphorin-F; Sema F; SEMA5A; SEMAF
Reconstitution	Please refer to the printed manual for detailed information.
Background	Semaphorin-5A (SEMA5A) is a member of the Semaphorin family of axon guidance molecules. SEMA5A is a 140 kDa protein. Class 5 Semaphorins are type I transmembrane glycoproteins with an N- terminal Sema domain and multiple juxtamembrane type 1 Thrombospondin (TSP) repeats within their extracellular domains. SEMA5A is expressed in neuroepithelial cells surrounding retinal axons, oligodendrocytes, the base of limb buds, the mesoderm surrounding cranial vessels , and the cardiac atrial septum and endocardial cushions, Human SEMA5A cDNA encodes a signal sequence, a extracellular domain (ECD), a transmembrane sequence and an cytoplasmic portion. SEMA5A mutations have been implicated in the genetic syndrome,cri-du-chat,while some polymorphisms may increase risk for neurodegenerative diseases such as Parkinson. The expression of SEMA5A may be upregulated in metastatic cancer cells and downregulated in autism.
Reactivity	Human
Tag	C-6His
Description	Recombinant Human Semaphorin 5A is produced by our Mammalian expression system and the target gene encoding Glu23-Thr765 is expressed with a 6His tag at the C-terminus.
Formulation	Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, 0.1mM EDTA, 0.05% Tween 20, pH 7.2.
Host	Human Cells
Accession Number	Q13591
Endotoxin Level	< 1.0 EU per ug as determined by the LAL method.
Mol Weight	84.7 kDa
Mw(kda)	84.7 kDa

Sequence Info	Glu23-Thr765

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 95 % as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10304021	PKSH033024	10ug	$129		Add to Cart
BHP10304021	PKSH033024	50ug	$375		Add to Cart

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