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Home / Proteins & Peptide

Recombinant Human Secreted Ly-6/uPAR-related protein 1(SLURP1)

SKU : BHP10505126

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP021784HUe1
Alternative Names	ARS component B ARS(component B)-81/S Anti-neoplastic urinary protein
Antigen	SLURP1
Tag	Tag-Free
Description	Has an antitumor activity. Was found to be a marker of late differentiation of the skin. Implicated in maintaining the physiological and structural integrity of the keratinocyte layers of the skin. In vitro down-regulates keratinocyte proliferation; the function may involve the proposed role as modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-7-dependent nAChR currents in an allosteric manner. In T cells may be involved in regulation of intracellular Ca2+ signaling. Seems to have a immunomodulatory function in the cornea. The function may implicate a possible role as a scavenger receptor for PLAU thereby blocking PLAU-dependent functions of PLAUR such as in cell migration and proliferation
Regulatory	RUO
Relevance	Has an antitumor activity. Was found to be a marker of late differentiation of the skin. Implicated in maintaining the physiological and structural integrity of the keratinocyte layers of the skin. In vitro down-regulates keratinocyte proliferation; the function may involve the proposed role as modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-7-dependent nAChR currents in an allosteric manner. In T cells may be involved in regulation of intracellular Ca2+ signaling. Seems to have a immunomodulatory function in the cornea. The function may implicate a possible role as a scavenger receptor for PLAU thereby blocking PLAU-dependent functions of PLAUR such as in cell migration and proliferation
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Protein Name	ARS component B; ARS(component B)-81/S; Anti-neoplastic urinary protein
Expression Region	23-103aa
Mol Weight	8.9 kDa
Nature	Recombinant
Protein Description	Full Length of Mature Protein

Involvement In Disease	Mal de Meleda (MDM)
Subcellular Location	Secreted
Uniprot	P55000, P55000
Database Links	HGNC:18746 OMIM:248300 KEGG:hsa:57152 STRING:9606.ENSP00000246515 UniGene:Hs.103505
Function	Has an antitumor activity
Research Area	Cardiovascular
Tissue Specificity	Granulocytes. Expressed in skin. Predominantly expressed in the granular layer of skin, notably the acrosyringium. Identified in several biological fluids such as sweat, saliva, tears, plasma and urine.
Weight	8.9 kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 85% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10505126	CSB-EP021784HUe1	1mg	$2632		Add to Cart
BHP10505126	CSB-EP021784HUe1	100ug	$744		Add to Cart
BHP10505126	CSB-EP021784HUe1	20ug	$472		Add to Cart

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