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Home / Proteins & Peptide

Recombinant Human RSK2 (N-GST tag)

SKU : BHP10900871

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z500351
Description	RSK2 is a member of the RSK (ribosomal S6 kinase) family that are growth factor-regulated serine/threonine kinases. RSK2 has been shown to mediate growth factor signaling via RAS and MAPK leading to the induction of CREB serine-133 phosphorylation and activation of gene expression . Mutations in RSK2 have been shown to be responsible for Coffin-Lowry syndrome (CLS) which is a X-linked disorder characterized by severe psychomotor retardation, facial and digital dysmorphisms, and progressive skeletal deformations .
Alternative Names	pp90RSK2 ; S6K-alpha3 ; RPS6KA3 ; HU-3 ; MAPKAPK1B ; CLS ; MRX19 ; ISPK-1 ; p90-RSK2
Tag	N-GST tag
Quantity	10 µg
Regulatory	RUO
Source	Insect cells
Host	Human
Biological Activity Comment	The specific activity of RSK2 was determined to be 157 nmol /min/mg as per activity assay protocol.

Weight	112.0 kDa

Format	Liquid 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Purity	70% - 90%
Storage	Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900871	Z500351	10µg	$361.11		Add to Cart

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