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Home / Proteins & Peptide

Recombinant Human ROR1 Protein (ECD, His Tag)

SKU : BHP10302741

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH030440
Description	A DNA sequence encoding the human ROR1 (NP_005003.2) (Met1-Glu403) was expressed with a polyhistidine tag at the C-terminus.
Alternative Names	dJ537F10.1;NTRKR1
Reconstitution	Please refer to the printed manual for detailed information.
Background	Receptor tyrosine kinase-like orphan receptor 1 (ROR1), also known as neurotrophic tyrosine kinase, it is a member of the ROR family within receptor tyrosine kinases (RTK) superfamily. Human ROR1 is a type I transmembrane protein with 937 amino acids (aa) in length. It contains a 29 aa signal sequence, a 377 aa extracellular domain (ECD), a 21 aa transmembrane segment, and a 510 aa cytoplasmic region. ROR1 expressed strongly in human heart, lung and kidney, but weakly in the CNS. At developmental stage, it expressed at high levels during early embryonic development. ROR1 has been shown to have very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo. It may act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling.
Reactivity	Human
Tag	C-His
Formulation	Lyophilized from sterile PBS, pH 7.4
Host	HEK293 Cells
Accession Number	NP_005003.2
Endotoxin Level	< 1.0 EU per ug as determined by the LAL method.
Mol Weight	43.4 kDa
Mw(kda)	43.4 kDa

Sequence Info	Met 1-Glu403

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 95 % as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10302741	PKSH030440	100ug	$855		Add to Cart
BHP10302741	PKSH030440	1mg	-		Add to Cart

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