ROR1 is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors that play a role in the control of most basic cellular processes including cell proliferation, differentiation, migration and metabolism . Many human breast cancers express the ROR1 protein and high-level expression of ROR1 in breast adenocarcinoma is associated with aggressive disease. Silencing expression of ROR1 in human breast cancer cell lines found to express this protein impaired their growth in vitro and also in immune-deficient mice .
Alternative Names
dJ537F10.1 ; NTRKR1
Tag
N-GST tag
Quantity
10 µg
Regulatory
RUO
Source
Insect cells
Host
Human
Biological Activity Comment
The specific activity of ROR1 was determined to be 0.2 nmol /min/mg as per activity assay protocol.
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.