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Home / Proteins & Peptide

Recombinant Human RIPK1 (N-GST tag)

SKU : BHP10900389

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z500338
Description	RIPK1 or Receptor Interacting Protein Kinase 1 is a serine/threonine kinase that was originally identified as interacting with the cytoplasmic domain of FAS. RIPK1 has been deemed as an important element in the signal transduction machinery that mediates programmed cell death. RIPK1 has been shown to interact with TRADD, TRAF1 TRAF2 and TRAF3 and TRADD can act as an adaptor protein to recruit RIPK1 to the TNFR1 complex in a TNF-dependent process . TNFalpha is capable of activating the noncanonical NF-kB pathway, but this activation of this pathway is negatively regulated by RIPK1 .
Alternative Names	RCK ; MAP3K19
Tag	N-GST tag
Quantity	10 µg
Regulatory	RUO
Source	Insect cells
Host	Human
Biological Activity Comment	The specific activity of RIPK1 was determined to be 3.5 nmol /min/mg as per activity assay protocol.

Weight	108.0 kDa

Format	Liquid 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Purity	70% - 90%
Storage	Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900389	Z500338	10µg	$694.44		Add to Cart

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