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Recombinant Human Receptor-type tyrosine-protein phosphatase-like N(PTPRN),partial

SKU : BHP10502891

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-YP613703HU
Alternative Names	Islet cell antigen 512, ICA 512, Islet cell autoantigen 3, PTP IA-2, Islet cell antigen 512 ; ICA 512 ; Islet cell autoantigen 3 ; PTP IA-2
Antigen	PTPRN
Tag	N-terminal 6xHis-tagged
Regulatory	RUO
Relevance	Implicated in neuroendocrine secretory processes. May be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions. Seems to lack intrinsic enzyme activity. May play a role in the regulation of secretory granules via its interaction with SNTB2.
Source	Yeast
Abbreviation	PTPRN
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Protein Name	Recommended name: Receptor-type tyrosine-protein phosphatase-like N; Short name= R-PTP-N; Alternative name(s): Islet cell antigen 512; Short name= ICA 512; Islet cell autoantigen 3; PTP IA-2
Expression Region	35-575aa
Mol Weight	59.3kDa
Nature	recombinant
Protein Description	Partial

Involvement In Disease	Autoantigen in insulin-dependent diabetes mellitus (IDDM).
Subcellular Location	Membrane, Single-pass type I membrane protein, Cytoplasmic vesicle, secretory vesicle membrane, Single-pass type I membrane protein, Perikaryon, Cell projection, axon, Cell junction, synapse, Cell membrane, Single-pass type I membrane protein, Endosome
Uniprot	Q16849, Q16849
Database Links	HGNC:9676 OMIM:601773 KEGG:hsa:5798 STRING:9606.ENSP00000295718 UniGene:Hs.89655
Function	Plays a role in vesicle-mediated secretory processes
Protein Families	Protein-tyrosine phosphatase family, Receptor class 8 subfamily
Research Area	Signal Transduction
Tissue Specificity	Expression is restricted to neuroendocrine cells. Found in pancreas, brain and pituitary.
Weight	59.27kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10502891	CSB-YP613703HU	500ug	$1298		Add to Cart
BHP10502891	CSB-YP613703HU	100ug	$470		Add to Cart
BHP10502891	CSB-YP613703HU	20ug	$250		Add to Cart

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