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Home / Proteins & Peptide

Recombinant Human Proheparin-binding EGF-like growth factor [Cleaved into: Heparin-binding EGF-like growth factor protein(HBEGF) (Active)

BHP10500196
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Contact us to order
Tel
+1 866.986.9598
Email
[email protected]
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Subcellular Location Heparin-binding EGF-like growth factor: Secreted, extracellular space
Uniprot Q99075, Q99075
Database Links

HGNC:3059

OMIM:126150

KEGG:hsa:1839

STRING:9606.ENSP00000230990

UniGene:Hs.592942
Function Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.
Pathway ErbB signaling pathway; Estrogen signaling pathway
Research Area Cancer
Weight 9.7 kDa
Buffer 0.2 µm filtered 20 mM PB, pH 7.4, 130 mM NaCl,lyophilized
Purity >97% as determined by SDS-PAGE and HPLC.
Storage Buffer 0.2 μm filtered 20 mM PB, pH 7.4, 130 mM NaCl ,lyophilized
Immunogen Species Homo Sapiens (Human)
SKU Supplier No. Size Your price Quantity
BHP10500196 CSB-AP002651HU 500ug $1308
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BHP10500196 CSB-AP002651HU 100ug $584
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BHP10500196 CSB-AP002651HU 10ug $142
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