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Home / Proteins & Peptide

Recombinant Human Programmed cell death 1 ligand 1(CD274),partial (Active)

BHP10506577
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Contact us to order
Tel
+1 866.986.9598
Email
[email protected]
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Subcellular Location Isoform 1: Cell membrane, Single-pass type I membrane protein, SUBCELLULAR LOCATION: Isoform 2: Endomembrane system, Single-pass type I membrane protein
Uniprot Q9NZQ7
Database Links

HGNC:17635

OMIM:605402

KEGG:hsa:29126

STRING:9606.ENSP00000370989

UniGene:Hs.521989
Function Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.
Protein Families Immunoglobulin superfamily, BTN/MOG family
Research Area Cancer
Tissue Specificity Highly expressed in the heart, skeletal muscle, placenta and lung. Weakly expressed in the thymus, spleen, kidney and liver. Expressed on activated T- and B-cells, dendritic cells, keratinocytes and monocytes.
Purity Greater than 85% as determined by SDS-PAGE.
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
Storage Buffer Tris-based buffer，50% glycerol
Immunogen Species Homo Sapiens (Human)
SKU Supplier No. Size Your price Quantity
BHP10506577 CSB-MP878942HU1 100ug $428
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BHP10506577 CSB-MP878942HU1 20ug $228
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