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Recombinant Human Probable JmjC domain-containing histone demethylation protein 2C(JMJD1C),partial

SKU : BHP10504784

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP624030HU
Description	Probable histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May be involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes
Alternative Names	Jumonji domain-containing protein 1C, Thyroid receptor-interacting protein 8, Jumonji domain-containing protein 1C Thyroid receptor-interacting protein 8
Tag	N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged
Regulatory	RUO
Relevance	Probable histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May be involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes
Source	E.coli
Abbreviation	JMJD1C
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Protein Name	Recommended name: Probable JmjC domain-containing histone demethylation protein 2C; EC= 1.14.11.-; Alternative name(s): Jumonji domain-containing protein 1C; Thyroid receptor-interacting protein 8; Short name= TR-interacting protein
Expression Region	2274-2498aa
Mol Weight	45.5kDa
Nature	Recombinant
Protein Description	Partial

Subcellular Location	Nucleus
Uniprot	Q15652, Q15652
Database Links	HGNC:12313 OMIM:604503 KEGG:hsa:221037 STRING:9606.ENSP00000382204 UniGene:Hs.413416
Function	Probable histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May be involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes (By similarity).
Protein Families	JHDM2 histone demethylase family
Research Area	Epigenetics and Nuclear Signaling
Weight	45.5 kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10504784	CSB-EP624030HU	1mg	$1812		Add to Cart
BHP10504784	CSB-EP624030HU	100ug	$419		Add to Cart
BHP10504784	CSB-EP624030HU	20ug	$224		Add to Cart

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