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Home / Proteins & Peptide

Recombinant Human POU domain class 2-associating factor 1(POU2AF1)

SKU : BHP10501308

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP620973HU
Alternative Names	B-cell-specific coactivator OBF-1BOB-1OCA-BOCT-binding factor 1
Tag	N-terminal 6xHis-tagged
Regulatory	RUO
Relevance	Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers.
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Expression Region	1-256aa
Mol Weight	31.4kDa
Nature	recombinant
Protein Description	Full Length

Involvement In Disease	A chromosomal aberration involving POU2AF1/OBF1 may be a cause of a form of B-cell leukemia. Translocation t(3;11)(q27;q23) with BCL6.
Subcellular Location	Nucleus
Uniprot	Q16633, Q16633
Database Links	HGNC:9211 OMIM:601206 KEGG:hsa:5450 STRING:9606.ENSP00000376786 UniGene:Hs.654525
Function	Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers.
Protein Families	POU2AF1 family
Research Area	Transcription
Tissue Specificity	B-cell specific.
Weight	31.5kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10501308	CSB-EP620973HU	1mg	$1812		Add to Cart
BHP10501308	CSB-EP620973HU	100ug	$419		Add to Cart
BHP10501308	CSB-EP620973HU	20ug	$224		Add to Cart

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