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Home / Proteins & Peptide

Recombinant Human Poliovirus receptor-related protein 4(NECTIN4),partial

SKU : BHP10502721

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-YP822274HU
Alternative Names	Ig superfamily receptor LNIRPoliovirus receptor-related protein 4
Tag	N-terminal 6xHis-tagged
Regulatory	RUO
Relevance	Ses to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with PVRL2/nectin-1. Does not act as receptor for alpha-herpesvirus entry into cells.
Source	Yeast
Abbreviation	PVRL4
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Protein Name	Recommended name: Poliovirus receptor-related protein 4; Alternative name(s): Ig superfamily receptor LNIR; Nectin-4; Cleaved into the following chain: 1. Processed poliovirus receptor-related protein 4
Expression Region	32-349aa
Mol Weight	36.1kDa
Nature	recombinant
Protein Description	Partial

Involvement In Disease	Ectodermal dysplasia-syndactyly syndrome 1 (EDSS1)
Subcellular Location	Cell membrane, Single-pass type I membrane protein, Cell junction, adherens junction, Note=Colocalizes with AFDN at cadherin-based adherens junctions (PubMed:11544254), SUBCELLULAR LOCATION: Processed poliovirus receptor-related protein 4: Secreted
Uniprot	Q96NY8, Q96NY8
Database Links	HGNC:19688 OMIM:609607 KEGG:hsa:81607 STRING:9606.ENSP00000356991 UniGene:Hs.492490
Function	Seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry into cells.; FUNCTION
Pathway	Adherens junction
Protein Families	Nectin family
Research Area	Cell Adhesion
Tissue Specificity	Predominantly expressed in placenta. Not detected in normal breast epithelium but expressed in breast carcinoma.
Weight	36.1kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10502721	CSB-YP822274HU	500ug	$1298		Add to Cart
BHP10502721	CSB-YP822274HU	100ug	$470		Add to Cart
BHP10502721	CSB-YP822274HU	20ug	$250		Add to Cart

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