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Recombinant Human Platelet-derived growth factor subunit B(PDGFB)

BHP10506878
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Involvement In Disease Basal ganglia calcification, idiopathic, 5 (IBGC5)
Subcellular Location Secreted
Uniprot P01127
Database Links

HGNC:8800

OMIM:190040

KEGG:hsa:5155

STRING:9606.ENSP00000330382

UniGene:Hs.1976
Function Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin
Pathway Jak-STAT signaling pathway; MAPK signaling pathway; PI3K-Akt signaling pathway; Focal adhesion; Gap junction; Regulation of actin cytoskeleton; Ras signaling pathway; Phospholipase D signaling pathway; Rap1 signaling pathway
Protein Families PDGF/VEGF growth factor family
Research Area Cancer
Tissue Specificity Expressed at high levels in the heart, brain (sustantia nigra), placenta and fetal kidney. Expressed at moderate levels in the brain (hippocampus), skeletal muscle, kidney and lung.
Purity Greater than 90% as determined by SDS-PAGE.
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
Storage Buffer Tris-based buffer，50% glycerol
Immunogen Species Homo Sapiens (Human)
SKU Supplier No. Size Your price Quantity
BHP10506878 CSB-EP017709HUc7 1mg $2062
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BHP10506878 CSB-EP017709HUc7 100ug $480
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BHP10506878 CSB-EP017709HUc7 20ug $256
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