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Home / Proteins & Peptide

Recombinant Human Plasma Kallikrein/KLKB1 Protein (His Tag)

SKU : BHP10303913

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH032901
Description	Recombinant Human Plasma kallikrein is produced by our Mammalian expression system and the target gene encoding Gly20-Ala638 is expressed with a 6His tag at the C-terminus.
Alternative Names	Plasma kallikrein;Fletcher factor;Kininogenin;Plasma prekallikrein;KLKB1;KLK3
Reconstitution	Please refer to the printed manual for detailed information.
Background	KLKB1 is a 638 amino acids protein that belongs to the peptidase S1 family and plasma kallikrein subfamily. It contains a peptidase S1 domain and four apple domains. The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin. It participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation.Plasma prekallikrein deficiency causes a prolonged activated partial thromboplastin time in patients.
Reactivity	Human
Tag	C-6His
Formulation	Supplied as a 0.2 um filtered solution of 20mM TrisHCl,150mM NaCl,10% Glycerol,pH8.0.
Host	Human Cells
Accession Number	P03952
Endotoxin Level	< 1.0 EU per ug as determined by the LAL method.
Mol Weight	70.2 kDa
Mw(kda)	70.2 kDa

Sequence Info	Gly20-Ala638

Shipping	This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stotage Note	Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Purity	> 95 % as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10303913	PKSH032901	10ug	$275		Add to Cart
BHP10303913	PKSH032901	50ug	$525		Add to Cart

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