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Home / Proteins & Peptide

Recombinant Human PKN2/PRK2 (N-GST tag)

SKU : BHP10900032

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z500324
Description	PKN2 (also known as PRK2) is a Rho effector and a member of the protein kinase C superfamily of serine/threonine kinases. PKN2 is an essential regulator of both entry into mitosis and exit from cytokinesis in HeLa S3 cells . PKN2 is required for abscission of the midbody at the end of the cell division cycle and for phosphorylation and activation of Cdc25B, the phosphatase required for activation of mitotic cyclin/Cdk1 complexes at the G2/M transition. C-terminus of PKN2 could be a potential drug target for effector-specific pharmacological intervention of Rho-medicated biological processes .
Alternative Names	PRKCL2 ; PKN2 ; PRK2 ; PAK2 ; Pak-2 ; PRO2042 ; MGC71074 ; MGC150606
Tag	N-GST tag
Quantity	10 µg
Regulatory	RUO
Source	Insect cells
Host	Human
Biological Activity Comment	The specific activity of PKN2/PRK2 was determined to be 74 nmol /min/mg as per activity assay protocol.

Weight	145.0 kDa

Format	Liquid 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Purity	70% - 90%
Storage	Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900032	Z500324	10µg	$361.11		Add to Cart

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