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Home / Proteins & Peptide

Recombinant Human PKN1/PRK1 (N-GST tag)

SKU : BHP10900452

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z500323
Description	PKN1/PRK1 belongs to the protein kinase C superfamily which is activated by Rho family of small G proteins. PKN1/PRK1 is known to mediate the Rho-dependent signaling pathway and it can be activated by phospholipids and by limited proteolysis . PDPK1/PDK may also mediate insulin signals to the actin cytoskeleton and the proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggest its role in signal transduction related to apoptosis. PKN1/PRK signaling stimulates AR activity in the presence of adrenal androgens and in the presence of an AR antagonist .
Alternative Names	PRK1 ; DBK ; PKN1 ; PKN ; MGC46204 ; PAK1 ; PRKCL1 ; PKC-L1
Tag	N-GST tag
Quantity	10 µg
Regulatory	RUO
Source	Insect cells
Host	Human
Biological Activity Comment	The specific activity of PKN1/PRK1 was determined to be 30 nmol /min/mg as per activity assay protocol.

Weight	115.0 kDa

Format	Liquid 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Purity	70% - 90%
Storage	Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900452	Z500323	10µg	$361.11		Add to Cart

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