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Home / Proteins & Peptide

Recombinant Human PKC theta (N-GST tag)

SKU : BHP10901001

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z500320
Description	Protein Kinase C, theta (PKC?) is important component in the intracellular signaling cascade . Recent studies have suggested that local accumulation of fat metabolites inside skeletal muscle may activate a serine kinase cascade involving PKC-theta leading to defects in insulin signaling and glucose transport in skeletal muscle . Insulin resistance plays a primary role in the development of type 2 diabetes and may be related to alterations in fat metabolism. PKC-theta is a crucial component mediating fat-induced insulin resistance in skeletal muscle and is a potential therapeutic target for the treatment of type 2 diabetes .
Alternative Names	PRKCT ; MGC126514 ; MGC141919 ; nPKC-theta ; PRKCQ
Tag	N-GST tag
Quantity	10 µg
Regulatory	RUO
Source	Insect cells
Host	Human
Biological Activity Comment	The specific activity of PKC?was determined to be 910 nmol /min/mg as per activity assay protocol.

Weight	110.0 kDa

Format	Liquid 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Purity	70% - 90%
Storage	Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10901001	Z500320	10µg	$361.11		Add to Cart

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