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Home / Proteins & Peptide

Recombinant Human PKC iota (N-GST tag)

SKU : BHP10900091

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z500317
Description	PKC? is a member of the protein kinase C family of serine-threonine kinases. The amino acid sequence of PKC? showed greatest homology to PKCzeta, with 72% identity overall rising to 84% in the catalytic domain. Protein kinase C iota (PKC?) has been implicated in Ras signaling and is a critical downstream effector of oncogenic Ras in the colonic epithelium. Transgenic mice expressing constitutively active PKC? in the colon are highly susceptible to carcinogen-induced colon carcinogenesis .
Alternative Names	PRKCI ; DXS1179E ; MGC26534 ; nPKC-iota
Tag	N-GST tag
Quantity	10 µg
Regulatory	RUO
Source	Insect cells
Host	Human
Biological Activity Comment	The specific activity of PKC?was determined to be 664 nmol /min/mg as per activity assay protocol.

Weight	98.0 kDa

Format	Liquid 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Purity	70% - 90%
Storage	Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900091	Z500317	10µg	$261.11		Add to Cart

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