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Home / Proteins & Peptide

Recombinant Human PI3K (p110 delta/p85 alpha) (N-His tag)

SKU : BHP10901196

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z500292
Description	PI3K (p110d/p85a) is a member of the PI3K family that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring . PI3K (p110d/p85a) plays a role in oncogenic transformation, and is consistently expressed at a high level in blast cells from AML. PI3K (p110d/p85a) can play a selective role in the amplification of phosphatidylinositol (3,4,5) trisphosphate (PIP3) levels that lead to neutrophil polarization, and regulates directional migration, but not random locomotion . PI3K (p110d/p85a) signaling pathway is involved in immune responses relevant to the pathogenesis of rheumatoid arthritis and other inflammatory diseases.
Alternative Names	GRB1 ; p85-ALPHA ; p110δ: p110δp85α: PIK3R1
Tag	N-His tag
Quantity	10 µg
Regulatory	RUO
Source	Insect cells
Host	Human
Biological Activity Comment	The specific activity of PI3K (p110d/p85a) was determined to be 50 nmol/min/mg as per activity assay protocol.

Weight	86.0 kDa, 111.0 kDa

Format	Liquid 50mM sodium, pHosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol.
Purity	70% - 90%
Storage	Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10901196	Z500292	10µg	$261.11		Add to Cart

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