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Home / Proteins & Peptide

Recombinant Human Phosphoinositide 3-kinase regulatory subunit 5(PIK3R5)

SKU : BHP10501446

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP841225HU
Alternative Names	PI3-kinase p101 subunitPhosphatidylinositol 4,5-bisphosphate 3-kinase regulatory subunit ,PtdIns-3-kinase regulatory subunitProtein FOAP-2,PtdIns-3-kinase p101p101-PI3K, PI3-kinase p101 subunitPhosphatidylinositol 4,5-bisphosphate 3-kinase regulatory subunit ; PtdIns-3-kinase regulatory subunitProtein FOAP-2 ; PtdIns-3-kinase p101p101-PI3K
Tag	N-terminal 6xHis-SUMO-tagged
Regulatory	RUO
Relevance	Regulatory subunit of the PI3K gamma complex. Required for recruitment of the catalytic subunit to the plasma mbrane via interaction with beta-gamma G protein dimers. Required for G protein-mediated activation of PIK3CG .
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Expression Region	1-494aa
Mol Weight	70.9kDa
Nature	recombinant
Protein Description	Full Length of Isoform 2

Involvement In Disease	Ataxia-oculomotor apraxia 3 (AOA3)
Subcellular Location	Nucleus, Cytoplasm, Cell membrane, Peripheral membrane protein
Uniprot	Q8WYR1, Q8WYR1
Database Links	HGNC:30035 OMIM:611317 KEGG:hsa:23533 STRING:9606.ENSP00000392812 UniGene:Hs.278901
Function	Regulatory subunit of the PI3K gamma complex. Required for recruitment of the catalytic subunit to the plasma membrane via interaction with beta-gamma G protein dimers. Required for G protein-mediated activation of PIK3CG (By similarity).
Pathway	PI3K-Akt signaling pathway; Apelin signaling pathway; cGMP-PKG signaling pathway; Oxidative Phosphorylation; Phospholipase D signaling pathway
Research Area	Signal Transduction
Tissue Specificity	Ubiquitously expressed with high expression in fetal brain compared to adult brain. Abundant expression is observed in cerebellum, cerebral cortex, cerebral meninges, and vermis cerebelli.
Weight	70.84kDa

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10501446	CSB-EP841225HU	1mg	$1812		Add to Cart
BHP10501446	CSB-EP841225HU	100ug	$419		Add to Cart
BHP10501446	CSB-EP841225HU	20ug	$224		Add to Cart

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