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Home / Proteins & Peptide

Recombinant Human p70S6K (N-His tag)

SKU : BHP10901228

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z500266
Description	p70S6K is responsible for the phosphorylation of 40S ribosomal protein S6 and is ubiquitously expressed in human adult tissues . p70S6K is activated by serum stimulation and this activation is inhibited by wortmannin and rapamycin. p70S6k activity undergoes changes in the cell cycle and increases 20-fold in G1 cells released from G0 . p70S6K activation requires sequential phosphorylations at proline-directed residues in the putative autoinhibitory pseudosubstrate domain, as well as threonine 389 a site phosphorylated by phosphoinositide-dependent kinase 1 (PDK-1).
Alternative Names	S6K1 ; STK14A ; RPS6KB1 ; p70-alpha ; p70(S6K)-alpha ; S6K ; PS6K
Tag	N-His tag
Quantity	10 µg
Regulatory	RUO
Source	Insect cells
Host	Human
Biological Activity Comment	The specific activity of p70S6K was determined to be 78 nmol /min/mg as per activity assay protocol

Weight	76.0 kDa

Format	Liquid 50mM NaPhosphate, pH7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.2mM DTT, 25% glycerol.
Purity	70% - 90%
Storage	Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10901228	Z500266	10µg	$361.11		Add to Cart

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