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Home / Proteins & Peptide

Recombinant Human NUAK1 (N-GST tag)

SKU : BHP10901096

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z500260
Description	NUAK1 or SNF1/AMP kinase-related kinase (SNARK) is a member of the NUAK family of SNF1-like kinase 1 that is also known as AMPK-related protein kinase 5 (ARK5). ARK5 is a tumor cell survival factor that is activated by AKT and acts as an ATM kinase under conditions of nutrient starvation . NUAK1 is highly expressed in heart and brain, and at lower levels in skeletal muscle, kidney, ovary, placenta, lung, and liver. NUAK1 is involved in tolerance to glucose starvation and suppresses Fas-induced apoptosis by phosphorylation of CASP6, thus suppressing the activation of the caspase and the subsequent cleavage of CFLAR .
Alternative Names	ARK5 ; KIAA0537
Tag	N-GST tag
Quantity	10 µg
Regulatory	RUO
Source	Insect cells
Host	Human
Biological Activity Comment	The specific activity of NUAK1 was determined to be50 nmol /min/mg as per activity assay protocol.

Weight	122.0 kDa

Format	Liquid 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Purity	70% - 90%
Storage	Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10901096	Z500260	10µg	$361.11		Add to Cart

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