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Home / Proteins & Peptide

Recombinant Human NIK (N-GST tag)

SKU : BHP10900879

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z500257
Description	NIK is a mitogen-activated protein kinase kinase kinase 14 (MAP3K14), which binds to TRAF2 and stimulates NF-kappaB activity. NIK shares sequence similarity with several other MAPKK kinases and participates in NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. NIK is expressed in primary human cells and in inflamed rheumatoid arthritis tissue and plays a selective role in signaling by the lymphotoxin-beta receptor . NIK is a therapeutic target in the immune and bone-destructive components of inflammatory arthritis.
Alternative Names	MAP3K14 ; HS ; HSNIK ; FTDCR1B
Tag	N-GST tag
Quantity	10 µg
Regulatory	RUO
Source	Insect cells
Host	Human
Biological Activity Comment	The specific activity of NIK was determined to be 8 nmol /min/mg as per activity assay protocol.

Weight	108.0 kDa

Format	Liquid 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Purity	70% - 90%
Storage	Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900879	Z500257	10µg	$361.11		Add to Cart

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