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Home / Proteins & Peptide

Recombinant Human ?-NGF/NGFB Protein (aa 122-23, Human Cells)(Active)

SKU : BHP10304241

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Elabscience Biotechnology Co.,Ltd

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Mfr.No.	PKSH033270
Alternative Names	Beta-Nerve Growth Factor; Beta-NGF; NGF; NGFB
Reconstitution	Please refer to the printed manual for detailed information.
Background	Human beta-Nerve Growth Factor (beta-NGF) was initially isolated in the mouse submandibular gland. It is composed of three non-covalently linked subunits alpha; beta; and gamma; it exhibits all the biological activities ascribed to NGF. It is structurally related to BDNF; NT-3 and NT-4 and belongs to the cysteine-knot family of growth factors that assume stable dimeric structures. beta-NGF is a neurotrophic factor that signals through its receptor beta-NGF; and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. beta-NGF also acts as a growth and differentiation factor for B lymphocytes and enhances B-cell survival. These results suggest that beta-NGF is a pleiotropic cytokine; which in addition to its neurotropic activities may have an important role in the regulation of the immune system. Human beta-NGF shares 90% sequence similarity with mouse protein and shows cross-species reactivity.
Reactivity	Human
Description	Recombinant Human beta-Nerve Growth Factor is produced by our Mammalian expression system and the target gene encoding Ser122-Arg239 is expressed.
Formulation	Lyophilized from a 0.2 um filtered solution of 20mM PB; 250mM NaCl; pH 7.0.
Host	Human Cells
Accession Number	P01138
Endotoxin Level	< 1.0 EU per ug as determined by the LAL method.
Bioactivity	Measured in a cell proliferation assay using TF?1 human erythroleukemic cells. The ED50 for this effect is 0.04-0.4 ng/ml.
Mol Weight	13.5 kDa
Mw(kda)	13.5 kDa

Sequence Info	Ser122-Arg239

Shipping	This product is provided as lyophilized powder which is shipped with ice packs.
Stotage Note	Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Purity	> 95 % as determined by reducing SDS-PAGE.

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHP10304241	PKSH033270	10ug	$37		Add to Cart
BHP10304241	PKSH033270	50ug	-		Add to Cart

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