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Home / Proteins & Peptide

Recombinant Human Neuronal calcium sensor 1(NCS1)

SKU : BHP10503604

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-EP008983HU
Alternative Names	Frequenin homolog, Frequenin-like protein, Frequenin-like ubiquitous protein, Frequenin homolog ; Frequenin-like protein ; Frequenin-like ubiquitous protein
Antigen	NCS1
Tag	N-terminal GST-tagged
Regulatory	RUO
Relevance	Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodulin. Stimulates PI4KB kinase activity. Involved in long-term synaptic plasticity through its interaction with PICK1. May also play a role in neuron differentiation through inhibition of the activity of N-type voltage-gated calcium channel
Source	E.coli
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Protein Name	Recommended name: Neuronal calcium sensor 1; Short name= NCS-1; Alternative name(s): Frequenin homolog; Frequenin-like protein; Frequenin-like ubiquitous protein
Expression Region	1-190aa
Mol Weight	48.7kDa
Nature	recombinant
Protein Description	Full Length

Subcellular Location	Golgi apparatus, Cell junction, synapse, postsynaptic cell membrane, postsynaptic density, Cytoplasm, perinuclear region, Cytoplasm, Cell membrane, Peripheral membrane protein, Membrane, Lipid-anchor
Uniprot	P62166, P62166
Database Links	HGNC:3953 OMIM:603315 KEGG:hsa:23413 STRING:9606.ENSP00000361475 UniGene:Hs.642946
Function	Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodulin (By similarity). Stimulates PI4KB kinase activity (By similarity). Involved in long-term synaptic plasticity through its interaction with PICK1 (By similarity). May also play a role in neuron differentiation through inhibition of the activity of N-type voltage-gated calcium channel (By similarity).
Protein Families	Recoverin family
Research Area	Neuroscience
Weight	48.49kD

Stotage Note	Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer	Tris-based buffer，50% glycerol
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer	Tris-based buffer,50% glycerol

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10503604	CSB-EP008983HU	1mg	$1812		Add to Cart
BHP10503604	CSB-EP008983HU	100ug	$419		Add to Cart
BHP10503604	CSB-EP008983HU	20ug	$224		Add to Cart

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