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Home / Proteins & Peptide

Recombinant Human NAP-2 (PPBP) (CXCL7)

SKU : BHP10900728

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z100725
Description	The chemokine neutrophil- activating peptide 2 (NAP-2) is a 70-amino acid residue polypeptide that is formed from platelet-derived precursors by proteolytic processing. Mature NAP-2 stimulates various effector functions of polymorphonuclear neutrophil granulocytes (PMN) including directed chemotactic migration, exocytosis of lysosomal enzymes and secondary granule contents, and up-regulation of adhesion receptors. NAP-2 has been assigned to a subfamily now termed alpha-chemokines. The alpha-chemokines contain four cysteine residues at highly conserved positions which enclose the core region of the molecules. The first two cysteines are separated by a single amino acid, forming a motif (CXC) that distinguishes the alpha-chemokine from the beta-chemokine subfamily, where these cysteines are in directly adjacent position.
Alternative Names	CTAP-III (precursor) ; Platelet basic protein ; C-X-C motif chemokine 7 ; Leukocyte-derived growth factor ; LDGF ; Macrophage-derived growth factor ; MDGF ; Small-inducible cytokine B7 ; SCYB7 ; TGB1 ; THBGB1 ; NAP2 ; CXCL7 ; PBP (parent molecule)
Quantity	10 µg
Regulatory	RUO
Source	E. coli
Host	Human
Endotoxin Level	<1.0 EU/μg of recombinant protein as determined by the LAL method.
Biological Activity Comment	Determined by its ability to chemoattract human monocytes using a concentration range of 2.0-40.0 ng/mL.

Weight	8.0 kDa

Description	A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Format	Lyophilized Powder Lyophilized from a 0.2 μm filtered 20 mM PB,100 mM NaCl solution pH 7.5.
Purity	>95% as determined by SDS-PAGE
Storage	The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

MSDS	Growth Factors, Cytokines & Kinases MSDS
Other	Growth Factor and Cytokine Brochure

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900728	Z100725	10µg	$169.44		Add to Cart

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