JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.
Loding Loading ....
Home / Proteins & Peptide

Recombinant Human Myosin regulatory light chain 2, ventricular/cardiac muscle isoform(MYL2),partial

BHP10501964
Contact us to order
Tel
+1 866.986.9598
Email
[email protected]
Get a Quote
Request More Infos
Order Now

Credit card payments now incur a 3% fee.

Contact us to order
Tel
+1 866.986.9598
Email
[email protected]
Get a Quote
Ask Merchant
Request More Infos
Sample Request
Involvement In Disease Cardiomyopathy, familial hypertrophic 10 (CMH10)
Subcellular Location Cytoplasm, myofibril, sarcomere, A band
Uniprot P10916, P10916
Database Links

HGNC:7583

OMIM:160781

KEGG:hsa:4633

STRING:9606.ENSP00000228841

UniGene:Hs.75535
Function Contractile protein that plays a role in heart development and function (By similarity). Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin binding sites to sustain thin filament activation as a means to fine-tune myofilament calcium sensitivity to force (By similarity). During cardiogenesis plays an early role in cardiac contractility by promoting cardiac myofibril assembly (By similarity).
Pathway Cardiac muscle contraction; Focal adhesion; Regulation of actin cytoskeleton; Leukocyte transendothelial migration; Apelin signaling pathway
Research Area Cardiovascular
Weight 21.9kDa
Stotage Note Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
Buffer Tris-based buffer，50% glycerol
Purity Greater than 90% as determined by SDS-PAGE.
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer Tris-based buffer,50% glycerol
Immunogen Species Homo Sapiens (Human)
Protocol-1
SKU Supplier No. Size Your price Quantity
BHP10501964 CSB-RP100574h 1mg $1812
Add to Cart
BHP10501964 CSB-RP100574h 100ug $419
Add to Cart
BHP10501964 CSB-RP100574h 20ug $224
Add to Cart