MYO3ß is a member of the Class III myosins that are actin-dependent motor proteins containing an amino-terminal kinase domain. MYO3ß contains a N-terminal kinase domain, followed by motor, neck, and tail domains. The MYO3ß gene generates a variety of splice variants that contain 1 or 2 calmodulin-binding (IQ) motifs in the neck domain and 1 of 3 domains in the tail domain. Northern blot analysis shows expression of a 7-kb MYO3ß transcript in the human retina but not in a RPE cell line . The MYO3ß gene transcript is also detected in the kidney, intestine and testis. The MYO3ß gene maps to chromosome 2q31.1-q31.2 by genomic sequence alignment.
Alternative Names
myosin IIIB
Tag
N-GST tag
Quantity
10 µg
Regulatory
RUO
Source
Insect cells
Host
Human
Biological Activity Comment
The specific activity of MYO3ßwas determined to be 85 nmol /min/mg as per activity assay protocol.
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Immunogen Species
Homo Sapiens (Human)
Reviews of Recombinant Human MYO3 beta (N-GST tag)