Myotonic Dystrophy Kinase-Related cdc42-binding kinase beta (MRCKß) belongs to the DMPK subfamily . The myotonic dystrophy kinase-related kinases and myotonic dystrophy kinase-related Cdc42 binding kinase (MRCK) are effectors of RhoA and Cdc42, respectively, where they are involved in actin cytoskeletal reorganization and neurite outgrowth . Effects of the repeat expansion on the DMPK gene may be responsible for muscle and heart features of Myotonic Dystrophy.
Alternative Names
CDC42BPB ; KIAA1124
Tag
N-GST tag
Quantity
10 µg
Regulatory
RUO
Source
Insect cells
Host
Human
Biological Activity Comment
The specific activity of MRCKß was determined to be 120 nmol /min/mg as per activity assay protocol.
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Immunogen Species
Homo Sapiens (Human)
Reviews of Recombinant Human MRCK beta (N-GST tag)