Myotonic Dystrophy Kinase-Related Cdc42-Binding Kinase a (MRCKa) is a Cdc42/Rac/Rho interactive/binding serine/threonine kinase with multiple functional domains . MRCK are effectors of RhoA and Cdc42, respectively, for actin reorganization. MRCKa is a critical regulator of signal transduction pathways in eukaryotic cells that are known principally for their role in regulating the cytoskeleton, and they do so by recruiting a variety of downstream effector proteins .
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Immunogen Species
Homo Sapiens (Human)
Reviews of Recombinant Human MRCK alpha (N-GST tag)