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Home / Proteins & Peptide

Recombinant Human MNK2 (N-GST tag)

SKU : BHP10900043

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z500232
Description	MNK2 (MAP kinase-interacting kinase 2) contains a conserved C-terminal ERK-interacting domain, a catalytic domain with homology to the calcium/calmodulin-dependent family of kinases, and putative MAP kinase phosphorylation sites located within the T loop of the kinase domain. MNK2 binds tightly to the growth factor-regulated MAP kinases, ERK1 and ERK2. ERK and p38 phosphorylate MNK2, which stimulates its in vitro kinase activity toward a substrate, eukaryotic initiation factor-4E (eIF-4E) . A yeast two-hybrid screen showed the Mnk2 protein interacted with the ligand-binding domain of estrogen receptor beta (ERbeta) .
Alternative Names	MKNK2 ; GPRK7
Tag	N-GST tag
Quantity	10 µg
Regulatory	RUO
Source	Insect cells
Host	Human
Biological Activity Comment	The specific activity of MNK2 was determined to be 93 nmol /min/mg as per activity assay protocol.

Weight	74.0 kDa

Format	Liquid 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Purity	70% - 90%
Storage	Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900043	Z500232	10µg	$361.11		Add to Cart

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