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Home / Proteins & Peptide

Recombinant Human MEKK6 (N-GST tag)

SKU : BHP10900673

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Applied Biological Materials (abm) Inc.

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Mfr.No.	Z500221
Description	MEKK6 or MAP3K6 (mitogen-activated protein kinase kinase kinase 6) is a member of the serine/threonine protein kinase family. MEKK6 was identified by its interaction with MAP3K5/ASK, a protein kinase and an activator of c-Jun kinase (MAPK7/JNK) and MAPK14/p38 kinase . MEKK6 cascades relay signals from the cell surface to the nucleus which result in gene transcription . MEKK6 activates the JNK and p38 pathway and induces apoptosis when overexpressed in stably transfected cells. MEKK6 transcript is expressed in several tissues, with the highest expression in heart and skeletal muscle.
Alternative Names	MAPKKK6 ; ASK2 ; MAP3K6
Tag	N-GST tag
Quantity	10 µg
Regulatory	RUO
Source	Insect cells
Host	Human
Biological Activity Comment	The specific activity of MEKK6 was determined to be10 nmol /min/mg as per activity assay protocol.

Weight	67.0 kDa

Format	Liquid 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Purity	70% - 90%
Storage	Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Immunogen Species	Homo Sapiens (Human)

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SKU	Supplier No.	Size	Your price	Quantity
BHP10900673	Z500221	10µg	$361.11		Add to Cart

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